Endocrine Abstracts

Differentiated Thyroid Cancer (DTC) is the most common malignant tumor in endocrinology, being the papillary subtype frequently found. The DTC is usually indolent and with a more favorable clinical prognosis of survival in 10 years, which has been diagnosed more frequently after the development and dissemination of complementary detection methods, according to the world literature. However, access to imaging exams with increasing resolving power makes a large number of low-ris...

Introduction: Self-care plays a fundamental role in the treatment and prevention of complications of diabetes mellitus (DM). The patient knowledge about DM and its potential complications are among the factors that are associated with treatment adherence. The process of understanding the disease provides the patient better communication with professionals, better metabolic and psychosocial results which may influence on their emotional well-being and quality of life.<p cla...

Introduction: Myxedematous coma is a rare endocrine emergency that settles in the absence of appropriate treatment for hypothyroidism for a long period. The severe and chronic reduction of serum thyroid hormones culminates in the insufficiency of compensatory mechanisms that maintain the physiological homeostasis of the organism. The clinical condition is severe, commonly associated with hypoxemia, hypercapnia, hypothermia, reduced cardiac output, and altered mental status.</p...

Introduction: The treatment of thyroid diseases with thionamides can cause agranulocytosis a potentially fatal side effect. The manifestations resulting from such a condition include, in most cases, infections that, if not treated immediately, have a high risk of septicemia. Therefore, the clinical presentation includes fever of unknown origin and infections such as pneumonia, tonsillitis, and abscesses. Most patients who do not receive immediate medical intervention progress ...

Introduction: Primary hypobetalipoproteinemia corresponds to a series of congenital disorders that have a variable incidence from 3.2% to less than 1 in 1 million, depending on the type of genetic mutation. The diseases that comprise it occur due to different types of mutations in genes that will encode important proteins at different stages of lipid metabolism. Individuals with determinant mutations of severe phenotypes, such as Bassen-Kornzweig syndrome, as known as Abetalip...